Further up I mentioned that I had seen an empty Layout list rather than what I had previously saved. 

I have now determined that this is the case when I run an application and EiffelStudio switches to Debugging Mode.

I adjusted my icon toolbar list to what I like to see at the moment in the Debugger and save it from the Debugger menus View menu (the one that at the moment was empty).

Huge frustration: when I end the Debugger and return to the project window, I check to see if the new save perhaps shows up among the ones I had previously saved.
HUGE FRUSTRATION:  all my previously saved Layouts are gone and only the Debugger Layout shows up [expletives removed].

Next step: prior to terminate EiffelStudio I intend to save the current project layout. 

Surprize: on the Save dialog all layout profiles are shown. I save an additional copy just in case. After saving I can again see the full list (including this latest save).